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History (12)
Depression symptoms and treatment among HIV infected and uninfected veterans.
Tracer imaging in lung cancer.
Emerging evidence on psychosocial effects of cancer cachexia: commentary on Oberholzer et al.
Aspergillus osteomyelitis: epidemiology, clinical manifestations, management, and outcome.
High-dose chemotherapy followed by stem cell transplantation in patients with resistant Waldenstrom's macroglobulinemia.
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WARGO, JENNIFER
One or more keywords matched the following items that are connected to
WARGO, JENNIFER
Item Type
Name
Concept
MAP Kinase Signaling System
Concept
Mitogen-Activated Protein Kinase 1
Concept
Mitogen-Activated Protein Kinase Kinases
Concept
MAP Kinase Kinase Kinases
Concept
Mitogen-Activated Protein Kinase 3
Concept
MAP Kinase Kinase 1
Academic Article
Systematic identification of signaling pathways with potential to confer anticancer drug resistance.
Academic Article
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E).
Academic Article
BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma.
Academic Article
Potential role of 5-aza-2'-deoxycytidine induced MAGE-A4 expression in immunotherapy for anaplastic thyroid cancer.
Academic Article
MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition.
Academic Article
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Academic Article
Case records of the Massachusetts General Hospital. Case 21-2013. A 68-year-old man with metastatic melanoma.
Academic Article
A melanocyte lineage program confers resistance to MAP kinase pathway inhibition.
Academic Article
Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function.
Academic Article
EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib.
Academic Article
The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition.
Academic Article
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.
Academic Article
TORC1 suppression predicts responsiveness to RAF and MEK inhibition in BRAF-mutant melanoma.
Academic Article
PDGFRa up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation.
Academic Article
A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors.
Academic Article
The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFa.
Academic Article
Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1a and oxidative phosphorylation in melanoma.
Academic Article
The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies.
Academic Article
YAP in MAPK pathway targeted therapy resistance.
Academic Article
Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial.
Academic Article
Interaction of molecular alterations with immune response in melanoma.
Academic Article
An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.
Academic Article
Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma.
Academic Article
Genetic and Genomic Characterization of 462 Melanoma Patient-Derived Xenografts, Tumor Biopsies, and Cell Lines.
Academic Article
Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in Braf-mutated melanoma.
Academic Article
Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy.
Academic Article
Microparticle-Delivered Cxcl9 Prolongs Braf Inhibitor Efficacy in Melanoma.
Search Criteria
Mitogen Activated Protein Kinase 1